A Northwest Indiana woman told she may never get pregnant again after being diagnosed with cancer is beating the odds. https://abc7.ws/2MGRmEh
Drugs that target G-protein coupled receptors or GPCR account for near 30% of the global market share of therapeutic drugs. The high interest and large market share are because of how important GPCRs are in many diseases. Right now, there are over 2000 different mutations in 55 GPCR genes that have been characterized and linked to over 60 human diseases. Based on how those mutations can change the functions of GPCRs, mutations can be divided into gain-of-function mutations and loss-of-function mutations.
–About me–
I am a computational chemist in the pharmaceutical industry. I created the Mole Man Chem channel to explain some basic medicinal and biochemistry concepts because I believe the best way to relearn a concept is through teaching.
Feel free to email me with any questions at molemanchem@gmail.com
–Video lists–
Medicinal chemistry playlist: https://www.youtube.com/watch?v=SNYb7E9oWO4&list=PLK7JMguNBXJOefOP5WFy9AUIsKReOD91I&t=0s
Drug discovery explained playlist: https://www.youtube.com/watch?v=0rMcD-_dGDI&list=PLK7JMguNBXJOBMkSsluR2926rtYLfRO7m
0:00 Overview
0:57 GPCR
4:52 GPCR mutations
8:25 GPCR mutation-caused disease treatment
