Steve Davis is working to bring an extraordinary vision to reality—the global elimination of the world’s most deadly and debilitating diseases. Davis is the president and CEO of PATH, a 40+ year-old, Seattle-based, global health-focused, non-governmental organization which works on vaccines, drugs, diagnostics, devices, and system and service innovations. In this talk, Davis lays out the “how to” of disease elimination calling on his diversity of experience as a former human-rights lawyer, a nationally-recognized technology business innovator, and social activist. Steve Davis, president and CEO of PATH, combines extensive experience as a technology business leader, global health advocate, and social innovator to accelerate great ideas and bring lifesaving solutions to scale. Prior to joining PATH in 2012, he served as director of Social Innovation at McKinsey & Company, CEO of the global digital media firm, Corbis, interim director of the Infectious Disease Research Institute, and he practiced law at the international law firm K&L Gates. Earlier, he worked extensively on refugee programs and policies, and Chinese politics and law. Mr. Davis is a lecturer on social innovation at the Stanford Graduate School of Business. He currently is a member of the Council on Foreign Relations, serves on the board of InterAction, and sits on several advisory groups, including the World Economic Forum’s Global Agenda Council on Social Innovation and the Clinton Global Initiative’s Global Health Advisory Board. He also serves as a trustee of the World Economic Forum’s Global Health Challenge. Mr. Davis earned his BA from Princeton University, his MA in Chinese studies from the University of Washington, and his law degree from Columbia University. He also studied at Beijing University. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx
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What is emphysema? Emphysema’s a type of chronic obstructive pulmonary disease (COPD) where the connective tissue in the lungs breaks down, obstructing the airways. Find our full video library only on Osmosis: http://osms.it/more.

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In this video, Dr Mike explains the difference between obstructive and restrictive respiratory disorders. He shows the anatomical changes that occur and highlights how various lung volumes and capacities are changed. This highlights why pulmonary function tests (PFTs) are important.
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Interstitial lung disease or ILD is an autoimmune condition of the lung. In some people, the body will attack itself and when it happens in the lung, it is a problem. Once the body begins to attack the lung, you become more short of breath. This video will tell you why.
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The World Health Organisation (WHO) has dubbed the anticipated next pandemic as “Disease X”, stating that it might already be “on its way”. watch the video for more details

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Pathology, symptoms, causes, risk factors and treatments of COPD. This video is available for instant download licensing here: https://www.alilamedicalmedia.com/-/galleries/narrated-videos-by-topics/respiratory-diseases/-/medias/288d2bd4-256d-459e-b3cd-284a0b4b5b75-chronic-obstructive-pulmonary-disease-copd-narrated-animation
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Chronic obstructive pulmonary disease, or COPD, is a PROGRESSIVE inflammatory lung disease characterized by INCREASING breathing difficulty. Other symptoms include cough, most commonly with mucus, chest tightness and wheezing. COPD develops as a result of LONG-TERM exposure to irritants such as smoke, chemical fumes or dusts, and may go UNNOTICED for years. Most people show symptoms after the age of 40 when the disease is already in its advanced stage.
The lungs consist of millions of air tubes or airways, called bronchi and bronchioles, which bring air in and out of the body. These airways end with tiny air sacs – the alveoli – where the gas exchange process takes place. REPEATED inhalation of irritants results in a CHRONIC inflammatory response which brings in a large amount of defensive cells along with inflammatory chemicals from the immune system. Inflammation of the airways causes them to thicken and produce mucus, NARROWING the air passage – this is known as CHRONIC BRONCHITIS. Inflammatory chemicals also dissolve alveolar walls, resulting in DESTRUCTION of the air sacs – this is EMPHYSEMA. COPD is, basically, a COMBINATION of these two conditions.
Tobacco smoking is accountable for about 90% of COPD cases. These include current, former smokers and people frequently exposed to second-hand smoke.
Extended contact with harmful chemicals such as fumes from burning fuel or dusts, at home or workplace, may also cause COPD.
Genetics has been implicated in a small number of cases. Notably, a condition known as alpha-1 antitrypsin deficiency, or AAT deficiency, has been shown to increase risks for COPD and other lung diseases. AAT protein protects the lungs from damaging effects of enzymes released during inflammation. Low levels of AAT make lung tissues more vulnerable to destruction when inflamed. While people with AAT deficiency may develop COPD even WITHOUT smoking or exposure to harmful irritants, AAT deficient smokers are at MUCH greater risks.
COPD is diagnosed based on symptoms, history of exposure to irritants and lung function tests. The major test for COPD is SPIROMETRY, in which the patient is asked to blow into a tube connected to a machine – a spirometer. Spirometry evaluates pulmonary functions by measuring the volume and the speed of air flow during inhalation and exhalation.
There is no cure for COPD but treatments can relieve symptoms, prevent complications and slow down progression of the disease. The first and most essential step to treatment is to stop smoking and/or improve air quality at home and workplace. These are also the most effective measures in preventing the disease.
Other treatments include:
-Medication: bronchodilators are used to widen the airways; steroids to relieve inflammation.
-Vaccination against flu and pneumococcal pneumonia: this is to prevent serious complications COPD patients may have with these respiratory infections.
-Supplemental oxygen: this can improve quality of life provided that the patient no longer smokes.
-Breathing exercises and other therapies as part of a pulmonary rehabilitation program.
-Finally, surgery may be performed for severe cases when other methods fail. Surgical procedures include bullectomy, lung volume reduction surgery, where damaged parts of the lung are removed; and lung transplant, where the entire diseased lung is replaced with a healthy lung from a deceased donor.
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Interstitial lung disease (ILD) causes scarring that damages lung tissue. Symptoms include shortness of breath, coughing and poor oxygen uptake.

For more information, visit https://uvahealth.com/services/pulmonary/interstitial-lung-disease

When someone is first diagnosed with interstitial lung disease or ILD, it’s actually an umbrella for a lot of different diseases, up to 200 of them. Depending on which type of ILD you have, your treatment can be very different. An example is in people who have idiopathic pulmonary fibrosis, or IPF. There are drugs that target the scaring process themselves, antifibrotic drugs that are available.

In contrast, people that have autoimmune conditions often respond to steroids or medications that suppress the immune system. These would be things that I wouldn’t use in an IPF patient but can be very useful in autoimmune conditions, or in conditions like sarcoidosis.

UVA has a really excellent interstitial lung disease program. It’s a big focus in our pulmonary division. The philosophy of the ILD clinic is to provide comprehensive, integrated care and develop a personalized treatment plan for each patient.
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Contamination of Water is a big problem and is associated with a lot of many Water Borne Diseases. This video will help you understand the Contamination of Water and Water Borne Diseases | Causes of Water Contamination | Prevention

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